Prepare the Baking Sheet: Line a baking sheet with parchment paper or lightly grease it with cooking spray.
Make the Glaze: In a small bowl, whisk together the honey, soy sauce, minced garlic, olive oil, Dijon mustard, thyme, salt, and pepper until well combined.
Place the Salmon: Put the salmon fillet on the prepared baking sheet, skin-side down.
Apply the Glaze: Brush half of the glaze mixture over the top of the salmon, ensuring it is evenly coated.
Bake the Salmon: Place the salmon in the preheated oven and bake for 15-20 minutes, or until the salmon flakes easily with a fork and is cooked through.
Broil for Extra Color: If desired, turn the oven to broil for the last 2-3 minutes to caramelize the glaze slightly.
Remove from Oven: Carefully remove the salmon from the oven and let it rest for a few minutes.
Garnish and Serve: Drizzle the remaining glaze over the salmon, garnish with fresh parsley, and serve with lemon wedges.